"We need the powers that be, and all the industries and all the networks, including E!, to help us with closing his pay gender gap", Dern told Seacrest.
"Will & Grace" star Debra Messing read E! for filth live on E!'s Golden Globes 2018 red carpet. I miss Catt Sadler.so we stand with her and that's something that can change tomorrow. "We stand with you Catt". "And when that new day finally dawns, it will be because of a lot of magnificent women, many of whom are right here in this room tonight - and some pretty phenomenal men - fighting hard to make sure that they become the leaders who take us to the time when nobody ever has to say #MeToo again".
Opening up about the hard decision to leave after just shy of 12 years on the network, Catt told PEOPLE: "Up until this point, I mean it really has been a dream job - Literally a dream job".
After they spoke up, Sadler - who quit in December after E! declined to pay her the same amount as "E!"
Messing wasn't the only star to bring up Sadler on the red carpet.
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Debra Messing calls out E! while on E!: "I was so shocked to hear that E! doesn't believing in paying their female co-hosts the same as their male co-hosts".
Messing added that it's time for "diversity", "intersectional gender parity" and "equal pay", which prompted her to turn her focus to E! "In fact, [Kennedy] was making close to double my salary for the past several years".
Sadler, who said on leaving E! that she didn't want to but had to "act in alignment with your beliefs", responded by saying: she was emotional that one of her "lifelong heroes" had validated her cause. Sadler said she repeatedly asked for a raise and was denied each time.
An E! spokeswoman referred CNNMoney to an earlier statement on the matter, which said the network "compensates employees fairly and appropriately based on their roles, regardless of gender".