Afghanistan's Defense ministry said Taliban militants killed at least 43 Afghan troops when they stormed the military base in southern Afghanistan, Reuters reported. "In the clashes, 43 have embraced martyrdom, 9 are wounded, 6 are missing and 2 have survived", Gen. Dawlat Waziri, spokesman for the MoD said.
It's the third assault of its kind this week, leaving at least 120 people dead.
In three out of the four assaults this week the Taliban used a Humvee vehicle as a bomb to blast their way into their targets.
"Chief of our Jamaat-ul-Ahrar Omar Khalid Khorasani, who sustained serious injuries in a recent U.S. drone strike in Afghanistan's Paktia province, succumbed to his injuries Wednesday evening", spokesman Asad Mansoor told AFP news agency by telephone.
Still, Nicholson continued to describe the fight in Afghanistan, America's longest-running war, as a stalemate.
The Taliban have been waging an insurgency for a decade and a half in an attempt to overthrow the government in Kabul.
"The enemy who thought they had scared us with the new Trump strategy have now been given a lesson".
The Western-backed government in Kabul is struggling to beat back insurgents in the wake of the exit of most North Atlantic Treaty Organisation forces in 2014. "They also had Humvees packed with explosives".
The base itself was left in ruins, officials said.
Considering the number of such vehicles at the Taliban's disposal, security officials and analysts fear this tactic will inflict heavier casualties on Afghanistan's already struggling security forces.
Afghan forces now control 59.7 percent of the country, up from 57.2 percent the previous quarter, according to SIGAR's assessment earlier this year.
"At least nine close associates of Khorasani were also killed in the strike", he added.