So, he could be there in this first Champions League match.
Gabriel Jesus will start in attack.
"We'll take things game by game and see where it takes us".
Captain Vincent Kompany remains sidelined with a calf injury.
Manchester City [1.43] have failed to record a victory in their last six away days at Europe's top table (W0-D3-L3), conceding 14 goals in the process. De Bruyne has emerged as a key player in the Citizen's midfield, earning a reputation as a highly gifted creative talent.
De Bruyne, with a more physical and hard-working approach that is likelier to win him friends in British football, could eventually end up mentioned in the same breath as Roy Keane, Patrick Vieira, Steven Gerrard and Frank Lampard, the mainstays in any "all-time Premier League XI" debate.
Feyenoord, playing in the Champions League group stage for the first time in 15 years, never seriously troubled City goalkeeper Ederson who had recovered sufficiently to play, albeit with a rugby-style scrum cap, after receiving a boot to the face Saturday from Liverpool's Sadio Mane.
He then slotted his second on the hour mark to seal only Tottenham's third win in 13 matches at Wembley where they lost two of their three Champions League home games last season.
Given Guardiola has coached Lionel Messi, Xavi and Andres Iniesta, that is high praise indeed but De Bruyne thinks his coach may be attempting to motivate him to keep up the fine form he has shown so far this season.
It was one way traffic for ninety minutes, with the away side enjoying 73% of the possession, and the home side constantly on their heels, defending wave after wave of City's relentless attack.
Although their last trip to the Netherlands produced their only loss there, a 3-1 defeat at Ajax in the group stage in 2012, it should make for a better trip this time around as this group of players now have experience in the tournament.