The company says Twitter notified it that the account had been compromised and are now investigating the situation.
The hashtag #BoycottMcDonalds might soon be trending along with #BoycottHawaii.
20 minutes later the tweet was deleted, and McDonald's claimed their account was "compromised".
McDonald's has blamed hackers after a tweet was posted from an official account slamming President Trump as "disgusting" and mocking his "tiny hands".
The president, who is frequently on Twitter, has not addressed the McDonald's tweet thus far.
The tweet laid into the President before calling for the reinstatement of Barack Obama.
It was re-tweeted almost 200 times and pinned to McDonald's profile before someone realised the account had been compromised.
The Tweet was even pinned for a time before the social-media cleanup crew could sweep it away-which, as noted above, would seem to dispel the suggestion that it was a employee error. Trump ordered McDonald's for the entire crew before takeoff.
He has previously said he is partial to a "fish delight", although by this he probably meant the McDonald's Filet-O-Fish.
You might think so if you started your day by checking the Twitter accounts of your favorite brands.
Michael Lott: "While we're talking about #BoycottHawaii can we add @McDonaldsCorp to the list?" Great! You are now officially on the #BoycottMcDonalds list! In a single week in 2013 alone, what appeared to be the same hacker or hackers took over both Burger King's and Jeep's Twitter accounts. So it is unsurprising that other Twitter users would lash out on him, either directly or through a company's social media accounts.
Yesterday, hundreds of Twitter accounts including Justin Bieber's and Forbes were hacked.
AUSTIN, TX - MARCH 14: Pandora fans at McDonald's booth during Pandora at SXSW 2017 on March 14, 2017 in Austin, Texas.