Clare Waight Keller, formerly the creative director at Chloé, will be taking on the future of the french fashion house as of May 2. Waight Keller will show her debut collection during Paris fashion week in October, and will be responsible for all the creative responsibilities at the house, including women's and men's ready-to-wear and accessories, as well as haute couture-a first for the designer.
Waight Keller joins Givenchy after six years as creative director of Richemont's fashion house Chloe, having pushed up sales of its floaty, romantic, 1970s-influenced clothes. Tisci (who is widely expected to move to Versace), announced his departure from the brand in February.
Tisci, 43, is credited with reviving Givenchy by cultivating links with a long line of celebrities including Beyonce, Madonna and Kanye West and his wife Kim Kardashian.
By contrast, Waight Keller is known for her feminine and bohemian approach to design.
This morning, Givenchy confirmed Clare Waight Keller as its new artistic director.
A knitwear specialist, she made her name by turning Pringle of Scotland from a rather staid knitwear-maker into a fashion brand. She is the first woman to hold the position at the company, which is owned by LVMH.
This is the second high profile female hire in the previous year, following the appointment of Maria Grazia Chiuri at Dior.
In a statement, she said the "confident style" of label founder Hubert de Givenchy had "always been an inspiration".
Tisci's next role remains to be seen.